Long COVID Atlas › Glossary › Hypercoagulability
MechanismHypercoagulability
https://longcovidatlas.org/glossary/hypercoagulability
In plain language
What it is
A state where the blood clots more readily than it should.
Why it matters
It is part of the vascular picture in long COVID and connects to microclots, vessel-lining injury, and raised cardiovascular risk.
Think of it like
Blood that is too quick to set, like glue that hardens before you have finished using it.
For specialists
Formal definition
A pro-thrombotic shift in the balance between clot formation and breakdown, involving platelet activation, tissue factor, and impaired fibrinolysis.
Mechanism
Endothelial injury exposes tissue factor and activates platelets while fibrinolysis is impaired, favouring clot formation and seeding fibrinaloid microclots.
Sources
- Exploring hypercoagulability in post-COVID syndrome free full text ›