Long COVID Atlas › Glossary › Viral persistence
MechanismViral persistence
https://longcovidatlas.org/glossary/viral-persistence
In plain language
What it is
The idea that pieces of the virus, or the whole virus, linger in the body long after the infection seems over.
Why it matters
A lingering reservoir could keep the immune system and blood vessels switched on for months.
Think of it like
Embers that never fully went out, quietly keeping the fire alarm ringing.
For specialists
Formal definition
Persistence of SARS-CoV-2 RNA, antigen, or replication-competent virus in tissue reservoirs after acute infection.
Mechanism
Persistent antigen sustains immune activation and ongoing endothelial irritation.